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YH Chang

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YH Chang, PhD

Professor


National Yang Ming University

Institute of microbiology and Immunology


 

 

 


Contact

Address: Institute of Biotechnology in Medicine

National Yang-Ming University

No. 155, Sec. 2, Linong St., Taipei 112, Taiwan

Phone: 02-28267309

Fax: 02-28264092

E-mail: cyh@ym.edu.tw


Publication

  1. Chang YH, Ho KT, Lu SH, Huang CN and Shiau MY#. Regulation of glucose/lipid metabolism and insulin sensitivity by interleukin-4. International Journal of Obesity 2011. (SCI, in press)
  2. Tsai CF#, Shiau MY, Chang YH#, Wang YL, Huang TL, Liaw YC, Tsao SM, Yang TP, Yang SC, Lin DB*. Trends of mycobacterial clinical isolates in Taiwan. Transactions of the Royal Society of Tropical Medicine and Hygiene 105:148-52, 2011 (SCI; #equal contribution as the first author)
  3. Tsai CF, Lin DB, Chen SC, Chang YH, Chen CY, Lin JB, and Lin YJ. Seroepidemiology of hepatitis A virus infection among schoolchildren in Taiwan. Journal of Medical Virology 82:196-200, 2011 (SCI)
  4. Ho KT#, Shiau MY#, Chang YH#, Chen CM#, Yang SC and Huang CN. Association of IL-4 promoter polymorphisms in Taiwanese patients with type 2 diabetes mellitus. Metabolism 59: 1717-22, 2010. (SCI; #equal contribution as the first author)
  5. Chang YH, Yu CW, Lai LC, Tsao CH, Ho KT, Yang SC, Lee H, Cheng YW, Wu TC, and Shiau MY. Up-regulation of interleukin-17 expressions by human papillomavirus type 16 E6 in non-small cell lung cancer. Cancer 116: 4800-4809, 2010. (SCI)
  6. Yang SC#, Chang WJ#, Chang YH#, Tsai TS#, Yang TP, Juan CW, and Shiau MY*. Prevalence of antibiotic resistance and oxa carbapenemases genes in multidrug-resistant Acinetobacter baumannii isolates in central Taiwan. European Journal of Clinical Microbiology & Infectious Diseases 29: 601-604, 2010 (SCI, in press; #equal contribution)
  7. Lee WY#, Chang YH#, Lo MK, Chang CP, Yang SC, Yang TP, Ho KT, Juan CW, and Shiau MY. Polymorphisms of CTLA-4 and cytokine genes in Taiwanese patients with ankylosing spondylitis. Tissue Antigens 75: 119-126, 2010 (SCI; #equal contribution)
  8. Chang YH, Huang CN, and Shiau MY. Cytokines, metabolism, and type 2 diabetes mellitus. Journal of Biomedical & Laboratory Sciences 21: 112-118, 2009 (Invited review)
  9. Lai DS, Lin JB, Chang YH, Lin YJ, Chen CY, Chen SC, Yang SF, Yang CC, Chen WK, Lin DB*. Pediatric reference intervals for several biochemical analysts in school children in central Taiwan. Journal of Formosa Medical Association 108: 940-946, 2009 (SCI)
  10. Norman PJ, Abi-Rached L, Gendzekhadze K, Hammond JA, Moesta AK, Sharma D, Graef T, McQueen KL, Guethlein LA, Carrington CV, Chandanayingyong D, Chang YH, Crespí C, Saruhan-Direskeneli G, Hameed K, Kamkamidze G, Koram K, Layrisse Z, Matamoros N, Milà J, Park MH, Pitchappan RM, Ramdath D, Shiau MY, Stephens HAF, Struik S, Tyan D, Verity DH, Vaughan RW, Davis RW, Fraser PA, Riley EM, Ronaghi1 M, Parham1 P. Meiotic recombination generates rich diversity in NK cell receptor genes, alleles and haplotypes. Genome Research 19:757-769, 2009 (SCI)
  11. Cheng YW, Lee H, Shiau MY, Wu TC, Huang TT, and Chang YH*. Human papillomavirus type 16/18 up-regulates the expression of interleukin-6 and anti-apoptotic mcl-1 in non-small cell lung cancer. Clinical Cancer Research 200814:4705-4712, 2008 (SCI)
  12. Chang YH, I-Ling Lin, Tsay GJ, Yang TP, Shiau MY*. Elevated MMP-2 and MMP-9 Levels and activities in patients with rheumatoid arthritis and systemic lupus erythematosus. Clinical Biochemistry 41: 955-959, 2008 (SCI)
  13. Norman PJ, Abi-Rached L, Gendzekhadze K, Korbel D, Gleimer M, Rowley D, Bruno D, Carrington CVF, Chandanayingyong D, Chang YH, Crespí C, Saruhan-Direskeneli G, Fraser PA, Hameed K, Kamkamidze G, Koram KA, Layrisse Z, Matamoros N, Milà J, Park MH, Pitchappan RM, Ramdath D, Shiau MY, Stephens HAF, Struik S, Verity DH, Vaughan RW, Tyan D, Davis RW, Riley EM, Ronaghi M, Parham P*. Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans. Nature Genetics 39: 1092-1099, 2007 (SCI)
  14. Wang L#, Chang YH#, Lee YL, Shih CM, Hsu YT, Shen GH, Haung ML, Shiau MY. Autoantibodies against tumor suppressor gene p53 in pleural effusions of patients with tuberculosis pleurisy. Annals of Clinical Biochemistry 44:57-62, 2007. (SCI; #equal contribution)
  15. Shiau MY, Lo MK, Chang CP, Yang TP, Ho KT, and Chang YH*. Association of tumor necrosis factor-npromoter polymorphism with ankylosing spondylitis in Taiwan. Annals of the Rheumatic Diseases 66: 562-563, 2007. (SCI)
  16. Shiau MY, Huang CN, Yang TP, Hwang YC, Tsai KJ, Chi CJ, Chang YH*. Cytokine promoter polymorphisms in Taiwanese patients with Graves’ disease. Clinical Biochemistry 40:231-217, 2007. (SCI)
  17. Shiau MY, Tsai ST, Tsai KJ, Haung ML, HsuYT, Chang YH*.Increased circulatory MMP-2 and MMP-9 levels and activities in patients with type 1 diabetes mellitus. Mount Sinai Journal of Medicine 73:1024-1028, 2006. (SCI)
  18. Chang YH, Wang L, Lee MS, Cheng CW, Wu CY, and Shiau MY. Genotypic characterization of Helicobacter pylori cagA and vacA from biopsy specimens of patients with gastroduodenal diseases in Taiwan. Mount Sinai Journal of Medicine 73:622-626, 2006. (SCI)
  19. Shiau MY, Huang CN, Wu CY, and Chang YH*. Association of IL-10 A-592C and T-819C polymorphisms with type 2 diabetes mellitus. Human Immunology 66:1258-63, 2005. (SCI)
  20. Chu SC, Wang CP, Chang YH, Hsieh YS, Yang SF, Yang CJ, Su JM, Chiou HL*. Elevated cystatin C serum concentrations in patients with hepatic diseases of various severities. Clinica Chimica Acta 341: 133-138, 2004. (SCI)
  21. Chang YH*, Shiau MY, Tsai CT, and Micheal S. Lan. Autoantibodies against IA-2, GAD and Topoisomerase II in type 1 diabetes mellitus in Taiwan. Biochemical and Biophysical Research Communications 320:802-809, 2004. (SCI)
  22. Chang YH, Huang CN, Lee YL, and Shiau MY*. The C-174G promoter polymorphism of the il-6 gene that affects insulin sensitivity in Caucasians is not involved in the pathogenesis of Taiwanese type 2 diabetes mellitus. European Cytokine Network 15: 117-119, 2004. (SCI)
  23. Chang YH, Wu CH, Lee YL, Huang PH, Kao YL, and Shiau MY*. Evaluation of NMP22 as a clinical diagnostic marker for bladder cancer. Urology 64: 687-692, 2004. (SCI)
  24. Lee YL, Shih CM, Chiou HL, Shiau MY, and Chang YH*. Alteration of p53 autoantibodies in lung cancer patients undergoing chemotherapy. Clinica Chimica Acta 349: 87-96, 2004. (SCI)
  25. Shiau MY, Huang CN, Liao JH, and Chang YH*. Missense mutations in the human insulin promoter factor-1 gene are not a common cause of type 2 diabetes mellitus in Taiwanese. Journal of Endocrinological Investigation 27: 1076-80, 2004. (SCI)
  26. Shiau MY, Wu CY, Huang CN, Hu SW, Lin SJ, and Chang YH*. TNF-n polymorphisms and type 2 diabetes mellitus in Taiwanese patients. Tissue Antigens 61:393-397, 2003. (SCI)
  27. Chen QY, Jackson N, Vargas A, Chalew S, Rao J, Batzer M, Lan MS, Chang YH, Mokhashi M, Liu D. Identification of three genomic haplotypes 5’ to the human CD1D gene and their distribution in four ethnic groups. Tissue Antigens 62:442-448, 2003. (SCI)
  28. Chang YH, Haung ML, and Shiau MY*. Germline premature-termination mutations of p53 gene in a patient with gastric leiomyosarcoma. Hungkuang Journal 41: 149-155, 2003.
  29. Haung ML, Chang YH, Chang YS, and Shiau MY*. Temporal relationship between immune responses against topoisomerase I, topoisomerase II, p53, p16 and p27 and chemotherapeutic efficacy in cancer patients. Hungkuang Journal 42: 39-46, 2003.
  30. Hsu YT, Chang YH, and Shiau MY*. Absence of anti-p53 antibody in Taiwanese patients with type 1 diabetes mellitus. Hungkuang Journal 42: 47-55, 2003.
  31. Shiau MY, Kuo TM, Tsai CT, Chiou HL, Lee YL, Lin LF, and Chang YH*. Absence of anti-p53 antibody in Chinese patients with rheumatoid arthritis and systemic lupus erythematosus. Arthritis & Rheumatism 46:276, 2002. (SCI)
  32. Shiau MY, Chiou HL, Lee YL, Kuo TM and Chang YH*. Establishment of a consistent L929 bioassay system for TNF- quantitation to evaluate the effect of lipopolysaccharide, phytomitogens and cytodifferentiation agents on the cytotoxicity of TNF-n in attached human mononuclear cells. Mediators of Inflammation 10: 199-208, 2001. (SCI)
  33. Shiau MY, Tsai ST, Hwang J, Wu CY, and Chang YH*: Relationship between autoantibodies against glutamic acid decarboxylase, thyroglobulin/thyroid microsome and DNA topoisomerase II at the clinical manifestation of patients with type 1 diabetes mellitus in Taiwan. European Journal of Endocrinology 142: 577-585, 2000. (SCI)
  34. Chang YH, Hwang J, Shang HF, and Tsai ST*: Characterization of human dna topoisomerase II as an autoantigen recognized by patients with IDDM. Diabetes 45: 408-414, 1996. (SCI)