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Szu-Hao Kung


Szu-Hao Kung, Ph.D.

Associate Professor


Ph.D. in Microbiology and Immunology,

University of South Florida, .


B.S. in Medical Technology,

National Yang-Ming University,  


Assistant Professor and Associate Professor
Faculty of Biotechnology and Laboratory Science in Medicine,
Institute of Biotechnology in Medicine,
National Yang-Ming University

Postdoctoral fellow,
University of Pennsylvania,
Department of Pathology and Laboratory Medicine,
Philadelphia, USA
Research Interests
A. The molecular mechanisms of apoptotic and autophagic cell death caused by enterovirus infection, especially focusing on the activity of the viral proteases.
B. Investigation into the intracellular action of viral protease by nanotechnology, and the application of the fluorescent biosensor.


Selected Publications
Hsu YY, Liu YN, Lu WW, Kung SH. (2009). Visualizing and quantifying the differential cleavages of the eukaryotic translation initiation factors eIF4GI and eIF4GII in the enterovirus-infected cell. Biotechnol Bioeng. 104(6):1142-52.
Tsai MT, Cheng YH, Liu YN, Liao NC, Lu WW, Kung SH. (2009). Real-time monitoring of human enterovirus (HEV)-infected cells and anti-HEV 3C protease potency by fluorescence resonance energy transfer. Antimicrob Agents Chemother. 53(2):748-755.
Hsu YY, Liu YN, Wang W, Kao FJ, and Kung SH. (2007). In Vivo Dynamics of Enterovirus Protease Revealed by Fluorescence Resonance Emission Transfer (FRET) based on a novel FRET pair. Biochem Biophys Res Commun. 353, 939–945.
Kung SH, Wang SF, Huang CW, Hsu CC, Liu HF, Yang JY. (2007). Genetic and antigenic analyses of enterovirus 71 isolates in Taiwan during 1998-2005. Clin Microbiol Infect. 13(8):782-7.
Ghukasyan V, Hsu YY, Kung SH, Kao FJ. (2007). Application of fluorescence resonance energy transfer resolved by fluorescence lifetime imaging microscopy for the detection of enterovirus 71 infection in cells. J Biomed Opt. 12(2):024016.
Lu WW, Hsu YY, Yang JY, Kung SH. (2004). Selective inhibition of enterovirus 71 replication by short hairpin RNAs. Biochem Biophys Res Commun. 325(2):494-9.